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General Directions
Follow the directions for using this medicine provided by your doctor.To decrease the chance of stomach upset, this medicine is best taken with food. Take this medicine with a full glass of water. Do not lie down for 30 minutes after taking this medicine. STORE THIS MEDICINE at room temperature below 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. IF YOU MISS A DOSE OF THIS MEDICINE DO NOT take 2 doses at once.

Medical Uses
This medicine is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve pain and swelling (inflammation). It is used to treat arthritis, acute pain, and menstrual pain and discomfort.

Side Effects
SIDE EFFECTS that may occur while taking this medicine include stomach upset, weakness or nausea. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience itching or skin rash, swelling of the feet or ankles, unexpected weight gain. CONTACT YOUR DOCTOR IMMEDIATELY if you experience swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness; flu-like symptoms; sluggishness; yellowing of the skin or eyes; dark urine or pale stools; or unusual fatigue. CONTACT YOUR DOCTOR IMMEDIATELY AND STOP TAKING THIS MEDICINE if you notice any of the following serious side effects: black stools, persistent stomach/abdominal pain, or vomit that looks like coffee grounds, mental/mood changes, or very stiff neck. If you notice other effects not listed above contact your doctor.

Precautions
DO NOT TAKE THIS MEDICINE IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to aspirin or any medicine containing aspirin or to a nonsteroidal anti-inflammatory drug (such as piroxicam, ibuprofen, naproxen, sulindac). A severe reaction includes a severe rash, hives, breathing difficulties, or dizziness. If you have a question about whether you are allergic to this medicine or if a certain medicine is a nonsteroidal anti-inflammatory drug, contact your doctor or pharmacist. IF YOU EXPERIENCE difficulty breathing; tightness of chest; swelling of eyelids, face, or lips; or if you develop a rash or hives, tell your doctor immediately. Do not take any more doses of this medicine unless your doctor tells you to do so. DO NOT EXCEED THE RECOMMENDED DOSE or take this medicine for longer than prescribed without checking with your doctor. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. ALCOHOL WARNING: If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take this medicine or other pain relievers/fever reducers. This medicine may cause stomach bleeding. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain aspirin, ibuprofen, naproxen, or ketoprofen. Aspirin as prescribed by your doctor for reasons such as heart attack or stroke prevention (i.e., non-arthritis doses, between 81-325 mg per day) should be continued. Caution is advised when using this medicine in the elderly because they may be more sensitive to the side effects of this medicine, especially stomach bleeding and kidney effects. FOR WOMEN: IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during the first 6 months of pregnancy. It should not be used during the last 3 months of pregnancy. DO NOT BREAST-FEED while taking this medicine.

Missed Dose
If you miss a dose of this medicine and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. DO NOT take a double dose of this medication unless instructed by your doctor.

Storage
Store this medicine at room temperature - 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Keep this and all medications out of the reach of children.

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